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Endocrine Therapy in Breast Cancer
by William R. Miller, James N. Ingle · CRC Press · tapa dura · 400 pages
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Pages: 400 pagesAuthor: William R. Miller, James N. InglePublisher: CRC PressFormat: tapa duraLanguage: enRelease date: 8/3/2002ISBN: ISBN 9780824707873
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Synopsis of Endocrine Therapy in Breast Cancer
Este libro evalúa y describe las últimas estrategias para la supresión hormonal y el bloqueo en el manejo del cáncer de mama en etapa temprana y avanzada. Explora los efectos del tamoxifeno, los moduladores selectivos del receptor de estrógeno (SERM), los inhibidores de la aromatasa y su combinación en los cánceres de mama y los tejidos normales. Detalla técnicas modernas para la creación de perfiles moleculares, el monitoreo y la focalización, y ofrece métodos para identificar grupos de alto riesgo. Examina la toxicidad potencial de la terapia endocrina dirigida al receptor de estrógeno (ER) e investiga el desarrollo de la resistencia endocrina. También analiza enfoques neoadyuvantes y preoperatorios en la atención al paciente y revisa los mecanismos que conducen a fenotipos independientes de estrógeno.
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